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What Happens When You Mix Caffeine And Marijuana?
coffee decorated with cannabis leaves

If you mix caffeine and marijuana, you may experience stronger effects.

Caffeine and marijuana are two of the most commonly used psychoactive drugs in the world.

They each have their own unique effects, but when combined the overall experience can be different than when consuming them separately.

Caffeine is the chemical that gives coffee and tea their effects. It is a central nervous system stimulant, like other drugs such as amphetamine and cocaine.

Caffeine makes you feel more awake and focused, and can improve concentration. It can also make you feel anxious, prevent sleep, cause headaches and increase heart rate.

Marijuana is a plant with a wide range of effects. It can make you feel euphoric and “high”, but can also have side effects including increased anxiety, dizziness, and increased heart rate.

Mixing Caffeine and Marijuana

mixing-caffeine-marijuana
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When caffeine and marijuana are mixed, their effects combine to create different effects than when taken alone.

Caffeine works in the brain to stop users from feeling drowsy. It also provides the brain with a small dopamine reward, which can act to reinforce habitual consumption. Marijuana also rewards the brain by providing a small increase in dopamine.

As both substances act to enhance dopamine, they are believed to have a synergizing effect.

This means that each substance may be able to increase some of the effects of the other, according to Dr. Sergi Ferre, a senior investigator at the National Institute on Drug Abuse.

What Are The Drawbacks?

Since both marijuana and caffeine can produce anxiety in users, combining the two may cause levels of anxiety that are greater than if either substance were consumed on its own.

Both substances also increase heart rates. This may mean that when used together, heart rates may become elevated even more so than when used alone.

Caffeine may also be able to counteract some of the effects of marijuana. Some of the sleep-inducing effects that can occur with marijuana might be reduced if caffeine is consumed.

When mixing any two substances, it is important to consider the potential harms and work to minimize them.

Knowing your tolerance as well as your current state of health can help tremendously to reduce any adverse effects.

Studies on Caffeine and Marijuana

Studies on Caffeine and Marijuana
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There is not a lot of research into the effects of combining marijuana and caffeine specifically. However, current research suggests that marijuana and caffeine may work together in the body to enhance each other’s effects.

Enhanced Effects

MSX-3 is a drug that works very similarly to caffeine in the brain. Scientists have used MSX-3 in squirrel monkeys to evaluate how caffeine can influence the effects of marijuana.

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In the study, the researchers trained squirrel monkeys to pull a lever to administer themselves a dose of THC.

After being given MSX-3, the monkeys were observed to pull the lever less frequently, indicating that the THC had become more effective.

This suggests that caffeine might make the effects of marijuana stronger than they normally are.

Memory Deficits

According to a 2012 study published in the British Journal of Pharmacology, the combination of marijuana and caffeine can impact memory.

When used alone, marijuana causes impairments to short term memory while caffeine can improve memory deficits.

However, when used together, the researchers found that caffeine worsened the memory deficits from marijuana.

Overall, the relationships between caffeine and marijuana and how they interact in the body are complex and not well understood.

Until more studies are done, it’s important to use these substances responsibly and be cautious when mixing them.

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