CB1 / CB2 Receptors
Cannabinoids interact with pathways in the body known as receptors. Many receptors exist in the body, but cannabinoids interact specifically with two types.
The two types of cannabinoid receptors are called CB1 and CB2. Both are found throughout the body, but are most common in the brain and immune system. When cannabinoids activate CB1 or CB2 receptors, they change the way the body functions.
CB1 receptors are responsible for marijuana’s psychoactive effects. They are present in many areas of the brain and play a role in memory, mood, sleep, appetite and pain sensation.
CB2 receptors are responsible for marijuana’s anti-inflammatory effects. They are found in immune cells and work to reduce inflammation. Inflammation is an immune response and is believed to be a factor in many diseases and conditions.
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